I thought you might find this interesting. This paper references a lot of older papers that inspired my thinking about HST and the importance of mechanical load (without reference to effort). Here's a link to full text. https://www.mdpi.com/2073-4409/9/7/1658/htm
Whoa a Bryan post!! Cool, I'll check that out, I remember asking about the early research quite a while ago on here, cool to see it.
Good study What I find interesting, is simply that the S.A.I.D. principle applies to cellular adaptations as well as larger scale adaptations. Stress something, 'its' what naturally is stimulated to adapt. Stress the energy systems, they adapt, stress the mechanical/physical structures, they are stimulated to adapt to preserve the cell.