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>Lyle -- or anyone else out there in the know -- can you recommend a good book that discusses insulin's role in bodybuilding? Are you asking about the effects of insulin in general (i.e. as a hormone) or as an injectable? I'm assuming the first but can't be sure. I'll go from there. Most...

>Do you want insulin sensitivity on refeed days; does it matter if you take ECA on those day(s) or would it be advisable to lay off the stimulants? It sort of depends, believe it or not. To optimally drive carbs (and other nutrients) into the muscle, you want high muscle insulin...

I wrote: 2. EPA doesn't work through the hexosamine biosynthetic pathway as someone stated (the HBP is simply a nutrient sensing pathway in both muscle and fat cells which 'tells' the cell how it's doing on nutrients, by changes in glucose metabolism in the cell).  EPA works via the PPAR...

You actually want to be insulin resistant when dieting. It's only when you're massing (overeating) that insulin resistance (in the muscle cell) gets you into trouble. I doubt that oral glucosamine is causing insulin resistance, by the way. As I recall, the studies used infused glucosamine. Elzi...

Someone told me about this thread (and Bryan's been bugging me to post here anyhow) and I see my name is being taken in vain as usual.  ;) Couple of comments. 1. All of the studies on glucosamine and leptin are in vitro, that is, they add it to cell culture.  I highly (highly, highly) doubt...